Awsome affinity purification mass spectrometry (AP-MS)

A collection of resources regarding affinity purification mass spectrometry proteomics for the identification of protein-protein interactions.

Algorithms

Year Algorithm Publication Implementation
2006 SAI (socio-affinity index) Anne-Claude Gavin et al., Nature
2007 partial least squares based regression model Rob M Ewing et al., Mol Syst Biol
2007 PE (purification enrichment) Sean R. Collins et al., Molecular & Cellular Proteomics SMAD
2007 Hart G Traver Hart et al., BMC Bioinformatics SMAD
2008 Dice coefficient Bing Zhang et al., Bioinformatics SMAD
2008 PP-NSAF Mihaela E. Sardiu et al., PNAS
2009 CompPASS Mathew E.Sowa et al., Cell SMAD
2010 Decontaminator MathieLavallée-Adam et al. J. Proteome Res.
2011 MiST Stefanie Jäger et al., Nature mist
2011 HGScore K.G.Guruharsha et al., Cell SMAD
2011 SAINT Hyungwon Choi et al., Nature Methods SAINT
2015 SFINX Kevin Titeca et al. J. Proteome Res. SFINX

Datasets

Year Species Abstract Publication
2002 S.cerevisiae 725 bait proteins, one-step immuno-affinity purification based on the Flag epitope tag Yuen Ho et al., Nature
2002 S.cerevisiae tandem-affinity purification processed 1,739 genes Anne-Claude Gavin et al., Nature
2006 S.cerevisiae Genome-wide TAP–MS, first introduced Anne-Claude Gavin et al., Nature
2009 H.sapiens Human Deubiquitinating Enzyme Interaction Landscape(DUB) Mathew E.Sowa et al., Cell
2010 S.cerevisiae kinase and phosphatase interaction (KPI) network Ashton Breitkreutz et al., Science
2009 H.sapiens autophagy interaction network (AIN) Christian Behrends et al., Nature
2011 D.melanogaster a Drosophila protein interaction map (DPiM) K.G.Guruharsha et al., Cell
2012 S.cerevisiae membrane-protein complexes in yeast Mohan Babu et al., Nature
2014 H.sapiens A comprehensive chromatin-related protein-protein interaction map Edyta Marcon et al., Cell Reports
2015 H.sapiens BioPlex v1 Edward L. Huttlin et al., Cell
2015 H.sapiens Autism Spectrum Disorders related Jingjing Li et al., Cell Systems
2016 H.sapiens PPI mapping of 50 unannotated mitochondrial proteins Brendan J.Floyd et al., Molecular Cell
2016 H.sapiens Comprehensive mitochondrial sirtuin interactome Wen Yang et al., Cell
2017 H.sapiens BioPlex v2 Edward L. Huttlin et al., Cell
2017 E.coli Global landscape of cell envelope protein complexes Mohan Babu et al., Nature Biotech
2017 H.sapiens A Map of Human Mitochondrial Protein Interactions related to Neurodegeneration Ramy H.Malty et al., Cell Systems
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Q. (Johnson) Zhang
A computational biologist

Genomics/Transcriptomics/Proteomics/Single Cell RNA-seq/Biological Network/Systems Biology

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